Both have a girl who disguises herself as a boy; in both you can find various ikemen; and both are incredibly hilarious while also having a romantic storyline. You'll also probably end up getting SLS (second lead syndrome) both times, so beware.
both have the same atmosphere, though in Ouran we have hosts and in Mei-chan we have butlers. The comedy is pretty much the same, though Ouran is a little more on the comedy side, whereas Mei-chan is more romantic than Ouran. The girls in both dramas are orphans and a little awkward. They both have lovable characters.
Both are dramas about a girl who, due to unforeseen circumstances, has to disguise herself as a male and work in a completely-male environment. In the beginning of both dramas, the girl isn’t trying to pass as a boy, but is always mistaken as one and only purposely disguises herself once she has a debt to her boss. Both dramas have a hardworking, down-to-earth girl who tries to earn money to keep her family fed and out of debt.
The main girl ends up having to work in a Host Club to pay of the money she owes from breaking a valueable item. The male lead roles have the same personalities. A Romance takes place in where first impressions aren't that good. Vampire Host is darker than OHSHC however, But they have lots of similarities which will make you love them both.
Serinuma Kae is a chubby high school girl who loves BL manga. One day her beloved character dies, and the girl falls into depression. For a long time, she cannot even eat, which leads to significant weight loss. But to her own surprise, the updated Serinuma becomes very popular at school, and she immediately has four handsome admirers at once.