Wanting to save the house of her beloved grandmother from being sequestered, paranormal expert Carmel Monseratt and her “bebest” best friend Jerald “Jeje” Zee-Yan have decided to form a squad of ghostbusters with their misfits buddies Bagang, Ponzi, and Basha, in order to meet both ends. One day, when they no longer have customers due to their modus going viral, Carmel meets a rich architect and dashing eligible bachelor Jack Colmenares who wants her and her squad to exorcise his house of all the ghosts inside it – real malevolent ghosts! – in exchange for a hefty amount of money.
To save her family from being homeless and her father suffering from a heart condition, Mayen desperately agrees to take the offer of a Chinese matchmaker for a huge amount of money. In exchange, Mayen must submit herself as a Ghost Bride to a wealthy but dead Chinese man. This deal, however, happens to be a deadly curse when the deceased groom's ghost becomes jealous and possessive of Mayen. It begins to take a toll on her and the people close to her heart. Ultimately, Mayen must make a choice on how to save herself, and most especially her family