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This is the Chinese counterpart to the Korean variety show "Crime Scene". In this show, participates have to find who is the murderer among them in a mock crime scene. Later seasons feature some episodes with real locations or completely built sets, which leads to more immersive environments like the "Great Escape".
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Both are investigation related shows with very similar production styles. The main cast is very similar between both shows. The major difference is that Who's the Keyman investigates non-murder incidences.